pCPA Activity Overview

Status Total Negotiations Summary
Active Negotiations 49 Non-oncology: 31
Oncology: 18
Under Consideration for Negotiation 16 Non-oncology: 11
Oncology: 5
Completed Negotiations 760 With Letter of Intent: 655
Without agreement: 105
Negotiations That Were Not Pursued 108

pCPA activity in the last four weeks

Activity for the last four weeks. Please note that these updates may take one to two weeks to be processed.

Engagement letters issued in the last four weeks

Brand Name Manufacturer Indication Engagement Date
Wainua AstraZeneca Canada Inc. Polyneuropathy in hereditary transthyretin-mediated amyloidosis
Omlyclo Celltrion Healthcare Canada Ltd. Multiple Indications
Venclexta AbbVie Corporation In combination with Gazyva, for the treatment of patients with previously untreated chronic lymphocytic leukemia
Gazyva Hoffmann-La Roche Ltd. In combination with Venclexta, for the treatment of patients with previously untreated chronic lymphocytic leukemia
TBC (infliximab) Celltrion Healthcare Canada Ltd. Multiple Indications
Repatha Amgen Canada Inc. Atherosclerotic cardiovascular disease
Opdivo-Yervoy Bristol Myers Squibb Canada Inc. In neoadjuvant setting for resectable stage III melanoma.
Opdivo-Yervoy Bristol Myers Squibb Canada Inc. ​In combination, for the first-line treatment of adult patients with advanced (unresectable or metastatic) melanoma when patients progress during or within 6 months of adjuvant PD-1 therapy.
Cabtreo Bausch Health, Canada Inc. Acne Vulgaris
Ultomiris Alexion Pharma GmbH Generalized myasthenia gravis (gMG)

Negotiations completed in the last four weeks with a letter of intent

Brand Name Manufacturer Indication Engagement Date Close Date
Veklury Gilead Sciences Canada Inc. COVID-19 in hospitalized patients
Veklury Gilead Sciences Canada Inc. COVID-19 in non-hospitalized patients
Bimzelx UCB Canada Inc. Psoriatic Arthritis
Bimzelx UCB Canada Inc. Ankylosing spondylitis
Truqap AstraZeneca Canada Inc. Breast cancer, locally advanced or metastatic (HR-positive, HER2-negative)
Adcetris Pfizer Canada ULC Hodgkin's Lymphoma
Apretude ViiV Healthcare HIV-1 infection, pre-exposure prophylaxis
Orgovyx Sumitomo Pharma Canada, Inc. Advanced prostate cancer
Fulphila BGP Pharma ULC Febrile neutropenia in non-myeloid malignancies
Tagrisso AstraZeneca Canada Inc. In combination with pemetrexed and platinum-based chemotherapy for the first-line treatment of patients with locally advanced (not amenable to curative therapies), or metastatic NSCLC whose tumours have epidermal growth factor receptor (EGFR) exon 19 dele
Sohonos Ipsen Biopharmaceuticals Canada, Inc. Fibrodysplasia Ossificans Progressiva

Negotiations completed in the last four weeks without agreement

Brand Name Manufacturer Indication Engagement Date Close Date
Palynziq BioMarin Pharmaceutical Inc. Phenylketonuria
Tavneos Otsuka Canada Pharmaceutical Inc. Antineutrophil cytoplasmic antibody-associated vasculitis

Negotiations that pCPA decided not to pursue in the last four weeks

Brand Name Manufacturer Indication Close Date
No negotiations that pCPA decided not to pursue in the last four weeks